Zhang博士学术报告的通知,Nadin教授系列讲座的通

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报告题目:Microphysiological Systems for Emulating Human Tissues and Diseases报 告 人:Shrike Yu Zhang博士(哈佛大学医学院布莱根妇女医院)时 间:2018年8月30日下午15:00地 点:华南软物质科学与技术高等研究院324报告厅材料科学与工程学院华南软物质科学与技术高等研究院2018年8月28日报告摘要:Microphysiological systems are microfluidic three-dimensional miniature human tissue and organ models that recapitulate the important biological and physiological parameters of their in vivo counterparts. They have recently emerged as a viable platform for personalized medicine and drug screening. These biomimetic organoids are anticipated to replace the conventional planar, static cell cultures, and to bridge the gaps between the current pre-clinical animal models and the human body. In addition, multiple organoids may be channeled together through the microfluidics in a similar manner they arrange in vivo, providing the capacity to analyze interactions among these models. In this talk, I will discuss our recent efforts on developing integrated multi-organ-on-a-chip platforms formed by sophisticated microfluidics and bioengineered organoids, which can operate in a continual and automated manner over extended periods. I will also discuss a series of bioprinting strategies including sacrificial bioprinting, microfluidic bioprinting, and multi-material bioprinting, along with various cytocompatible bioink formulations, for the fabrication of biomimetic organoids. These platform technologies will likely provide new opportunities in constructing functional tissue and disease models with a potential extension into clinical therapeutics and precision therapy.报告人简介:Dr. Zhang received a B.Eng. in Biomedical Engineering from Southeast University, China in 2008, after which he then obtained a M.S. in Biomedical Engineering from Washington University in St. Louis and a Ph.D. in Biomedical Engineering at Georgia Institute of Technology and Emory University School of Medicine . Dr. Zhang then pursued postdoctoral training atBrigham and Women’s Hospital,Harvard Medical School, Harvard-MIT Division of Health Sciences and Technologies, and Wyss Institute for Biologically Inspired Engineering.Dr. Zhang is currently a Research Faculty at Harvard Medical School and Associate Bioengineer at the Brigham and Women’s Hospital. Dr. Zhang’s research is focused on innovating medical engineering technologies, including 3D bioprinting, organs-on-chips, microfluidics, biomedical imaging, and biosensing, to recreate functional tissues and their biomimetic models. In collaboration with a multidisciplinary team encompassing biomedical, mechanical, electrical, and computer engineers as well as biologists and clinicians, his laboratory seeks to ultimately translate these cutting-edge technologies into the clinics. He is an author of >120 publications and his scientific contributions have been recognized by >40 international, national, and regional awards. More information can be found on his website (www.shrikezhang.com).

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