关于开展2018年新增研究生指导教师遴选工作的通

报告题目Data-Driven Rational Biosynthesis Design: From Moleculesto Cell Factories报 告 人:胡黔楠 博士 中国科学院上海生命科学研究院研究员报告时间:2018年6月5日10:30 – 11:30 报告地点:华南理工大学大学城校区生物科学与工程学院B6-207欢迎广大师生踊跃参加!生物科学与工程学院2018年5月30日报告人简介:胡黔楠博士,中国科学院上海生命科学研究院研究员,计算生物学研究所细胞工厂设计研究组组长,科技部重点专项咨询委专家和指南评估专家,国家基金委杰青等项目评审专家。胡黔楠博士从事生物制造设计技术平台构建研究,创建了全球最大的生物制造产品数据库以及生物合成反应数据库,开发了数据驱动型一站式生物合成设计技术系统RxnFinder,打造了数据驱动型微生物细胞工厂研究新模式。在生物制造产品数据库、生物合成反应数据库、生物合成前体化合物挖掘、目标化合物选择、酶发现技术、生物合成途径设计、化合物生物合成潜力挖掘、微生物菌株优化、菌株理性选择、以及一站式设计技术集成等方面研究中作出了一系列原创性的工作。报告摘要:Microbial cell factories have a lot of important and promising applications in producing bulk chemicals, natural products, biofuels, and so on. The new bottleneck of microbial cell factory is how to design reaction, enzyme, and pathway, based on enormous biosynthesis data. Our team has been focused on the construction of data-driven biosynthesis design platform (www.rxnfinder.org), which is composed of the following sections: Biochemical reaction database (RxnFinder): our team manually curated more than 200,000 biochemical reactions, which are 10 times larger than the KEGG reactions, from more than 500,000 biosynthesis references retrieved from PubMed using more than 40 biosynthesis related keywords. More than 10 third party databases are linked, and more than 10 informatics methods are provided. Enzyme discovery (ECAssignment): a chemical transformation-based method (ECAssigner) is proposed for enzyme discovery using biochemical reaction difference fingerprints and reaction similarity. Biosynthetic pathway design (BioSynther): BioSynther tool was developed to design biosynthesis pathways between starting molecules and target molecules, in which users can interactively re-design biosynthetic pathways. One of the most promising applications of biosynthetic methods is to produce chemical products of high value from the ready-made chemicals. BioSynther is also developed to explore the biosynthetic potentials of precursor chemicals using BKM-react, Rhea, and more than 100,000 in house RxnFinder reactions manually curated. Cell -based pathway optimization platform (SynBioEcoli, EcoSynther, LifeSynther): Based on the comprehensive biosynthetic data curated above, whole-cell modelling methods are proposed to optimize heterogeneous biosynthetic pathways. The proposed data-driven one-stop informatics platform could be used as a useful tool in metabolic engineering, biosynthesis, and synthetic biology.

附件:图片 1 附件1-华南理工大学2018年拟备案学科名单.docx图片 2 附件2-华南理工大学专业学位类别目录.docx图片 3 附件3-各学院博士生指导教师遴选条件汇总.doc图片 4 附件4-华南理工大学新增博士生导师申请表.doc图片 5 附件5-博导申请人申报条件审核情况一览表.doc图片 6 附件6-各学院学术型硕士生导师遴选条件汇总.doc图片 7 附件7-申请学术型硕士生指导教师简况表.doc图片 8 附件8-分会表决通过的学术型硕导申报条件审核情况一览表.doc图片 9 附件9-专业学位研究生校内指导教师简况表.doc图片 10 附件10-专业学位硕士生校内导师名单汇总表.xls图片 11 附件11-专业学位研究生校外导师聘任审批表.doc图片 12 附件12-专业学位硕士生校外导师及指导学生名单汇总表.xls图片 13 附件13-分会会议纪要.doc图片 14 附件14-申请博、硕士生指导教师分会表决票及表决票汇总表.doc图片 15 附件15-申请博、硕士生指导教师分会通过上报汇总表.doc图片 16 附件16-学院申请博士生指导教师公示通知模板.docx图片 17 附件17-学院申请博士生指导教师公示情况报告模板.docx

附件:图片 18 2018年国庆节后第一天全日制硕士生上课情况.xls

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